WebThe use of neurons derived from induced pluripotent stem cells (iPSC) has led to deciphering convergent and pleiotropic neuronal synaptic phenotypes found in neurodevelopmental disorders such as autism spectrum disorders (ASD) and their associated syndromes. WebJan 14, 2024 · Aline Vitrac, Hany Goubran-Botros, Anne Danckaert, Jean-Yves Tinevez, Gwenaëlle André-Leroux, Ekaterina Atanasova, Nathalie Lemière, Anne Biton, Claire S. …
Altered spinogenesis in iPSC-derived cortical neurons from …
WebOct 28, 2024 · A schematic for iPSC modeling of neurological diseases. The logical path of modeling neurological diseases using patient-derived iPSCs mainly includes the following steps. First, iPSCs are generated from patients by reprogramming somatic cells using 4 Yamanaka factors, OCT4, SOX2, KLF4, and MYC. WebDec 1, 2014 · This pathway is known for playing a role in synapse formation and the balance of excitation and inhibition within the brain. In parallel, we identified the first mutations … tarsus pipeline
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WebJan 11, 2024 · Defective neuritogenesis is a contributing pathogenic mechanism underlying a variety of neurodevelopmental disorders. Single gene mutations in activity-dependent neuroprotective protein (ADNP) are... WebSep 17, 2024 · Our work is a thorough investigation and characterization of the pathophysiological changes in these IQSEC2 mutant hippocampal neurons and provides a platform for the development of precision... WebAline Vitrac About Work Works at Les Galets de l'Oracle Eaunes, Midi-Pyrenees, France College No schools to show High school No schools to show Photos See all photos Others Named Aline Vitrac See more Others With a Similar Name Aline Mello Aline Balduino Aline Guimaraes Alinne Cailana Aline Santana Li Ferreira Cabral Aline Silva clog\\u0027s ki