D threo pdmp supplements
WebIncubating B16 melanoma cells with an inhibitor of glucosylceramide (GlcCer) synthetase, D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-threo-PDMP), led … WebEnhances the apoptotic response to ionizing radiation by enhancing the ceramide signal. Alternative name: D,L-threo-PDMP . hydrochloride, DL-PDMP. Purity: ≥98% (TLC). Solubility: 25mg/ml soluble in 100% ethanol, DMSO or water (50°C, vortex or sonicate). Long Term Storage: -20°C. Catalog No. 50-201-2125 $328.04 / Each of 1 Qty Check …
D threo pdmp supplements
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Web4mM PDMP stck solution will be stable at refrigerator at least one month. The final concentration of PDMP will be 5–40 μM dependent on cell type and treatment periods … WebMar 23, 2015 · Application: DL-PDMP is a ceramide analog first prepared in a search for inhibitors of glucosylceramide synthase CAS Number: 73257-80-4 Purity: ≥98% …
WebNov 3, 1998 · Three other d - threo -PDMP analogues with various amine groups have been synthesized using the same methodology, including the more potent pyrrolidine … WebDL-threo-PDMP, Hydrochloride PDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this …
WebApr 11, 2006 · D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP) is a frequently used inhibitor of glycosphingolipid biosynthesis. However, some … WebDescription. This product is a glucosylceramide synthase inhibitor, an enzyme that is essential for the synthesis of a very large number of different glycolipids that are found in many organisms.1 PDMP has four possible …
WebD- threo -PDMP This product is a glucosylceramide synthase inhibitor, an enzyme that is essential for the synthesis of a very large number of different glycolipids that are found in many organisms. CUSTOMER SERVICE 814.355.1030 Toll Free: 800.342.3595 M … The D-threo isomer has been shown to be the active glucosyl ceramide synthetase … 2178 High Tech Road, State College, PA 16803 USA Phone: (814) 355-1030 • …
WebMar 4, 2024 · The commonly used sphingolipid inhibitors, myriocin (a ceramide inhibitor) and d -PDMP ( d -threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, a glycosphingolipid inhibitor), have shown therapeutic potential but their efficacy and their underlying mechanisms remain unclear. shower amazing bathroomWebd - threo -1-Phenyl-2-decanoylamino-3-morpholino-1-propanol ( d -PDMP) is a frequently used inhibitor of glycosphingolipid biosynthesis. However, some … shower and bathWebScientific Name:D,L-threo-PDMP Common Name:D,L-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl Activity: glucosylceramide synthase inhibitor Empirical Formula:C23H38N2O3•HCl CAS#:80938-69 … shower and bath clip artWebpropanol (D-PDMP) is an effective inhibitor of the gluco- syltransferase that makes glucosylceramide. Virtually all of the hundreds of naturally occurring glycolipids are formed from this primary glycolipid, so the inhibitor acts to lower their concentra- tions by the process of attrition (hydrolytic catabolism). shower and bath combo ideasWebPDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme. Synonym (s): DL-threo-PDMP, Hydrochloride, 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl Empirical Formula (Hill Notation): C23H38N2O3 · xHCl CAS Number: 80938-69-8 Molecular Weight: shower and bath aids for elderly peopleWebd-threo-PDMP is an inhibitor of the enzyme UGCG (glycosylceramide synthase) which is the intial step in the glycosylation of ceramide. Studies show that d-threo-PDMP … shower and bath caulkingWebDL-threo-PDMP C23H38N2O3 CID 11957678 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … shower and bath chairs